Fe3O4@SiO2/AEPTMS/Fe(OTf)3: An efficient superparamagnetic nanocatalyst for the protecting of alcohols

Document Type : Research Article


1 Institute of Nanoscience and Nanotechnology, University of Kashan, Iran

2 Department of Chemical Engineering, Islamic Azad University, Iranshahr Branch, Iranshahr, Iran


Fe3O4@SiO2/AEPTMS/Fe(OTf)3 is a stable, effective, and magnetic nanocatalyst easily prepared and characterized using FT-IR spectroscopy, SEM, TEM, and VSM techniques. This nanocatalyst was successfully applied for trimethylsilylation of numerous alcohols (primary, secondary, and tertiary alcohols) with hexamethyldisilazane in 1 ml dichloromethane at room temperature to their corresponding trimethylsilyl (TMS) ethers. Quick response times and a simple reprocessing procedure are two fascinating advantages of this nanocatalyst. This catalyst protects alcohols at 1.5 min, and turn-over frequency (TOF) values for the presented catalytic system have been estimated 833 h-1.

Graphical Abstract

Fe3O4@SiO2/AEPTMS/Fe(OTf)3: An efficient superparamagnetic nanocatalyst for the protecting of alcohols


  • Synthesis of Fe3O4@SiO2 / AEPTMS / Fe(OTf)3 as magnetic nanocatalyst.
  • Synthesis of fine spherical nanoparticles without agglomeration.
  • These nanocatalysts were used to protect the hydroxyl group in aromatic and linear alcohols.


Main Subjects

Copyright © 2023 The Author(s). Published by IROST.

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