Iranian Research Organization for Science and Technology Journal of Particle Science and Technology 2423-4087 5 2 2019 08 01 Ultrasonic synthesis of Zn(II) methionine and ZnO nanostructures as a new precursor for ZnO nanoparticles and in-vitro study 109 116 884 10.22104/jpst.2019.3551.1147 EN Rouzbeh Aghaei Hakkak Department of Chemical Technologies, Iranian Research Organization for Science and Technology (IROST), Tehran, Iran Maryam Ranjbar Department of Chemical Technologies, Iranian Research Organization for Science and Technology (IROST), Tehran, Iran 0000-0003-3445-613X Sara Mirzaie Department of Agriculture, Iranian Research Organization for Science and Technology (IROST), Tehran, Iran Journal Article 2019 04 16 Zinc(II) ions play a special role in biological systems. Methionine is a sulphur containing amino acid with IUPAC name 2-amino-4-(methylthio)butanoic acid. In this study, ultrasonic synthesis and characterization of nanostructured Zn(II) methionine (Zn-Meth) in two different solvents were investigated. The reaction of ZnCl₂ and methionine ligand under ultrasonic irradiation in both methanol and DMSO leads to the formation of nano-sized Zn(II) methionine complexes. Characterization of the Zn(II) complex was performed using elemental analysis, FT-IR spectroscopy, X-ray powder diffraction (XRD), thermal gravimetry (TGA), field emission scanning electron microscopy (FE-SEM), and energy-dispersive X-ray spectroscopy (EDS). The nano Zn-Meth complex, [Zn(CH₃SCH₂CH₂CHNH₂COOH)₂]_n, was then used as a precursor to obtaining the nano ZnO particle. An <em>in-vitro</em> study of the everted gut sac was also done on this complex to measure the uptake amount of zinc. The results showed that the nano-sized Zn-Meth has a higher absorption compared to its commercial and inorganic forms. https://jpst.irost.ir/article_884_170c944978496731ba71f34c25826a34.pdf